ITT Engineered Valves
Pure-Flo Chromatography Valve
The Pure-Flo Chromatography Valve machines the cluster of diaphragm valves that connects a chromatography column to process piping into one integral block. A single compact assembly does the work of several individual valves while sharply reducing internal surfaces and hold-up volume.
Product Benefits
- Fewer welds and dead legs: Building column connections from discrete valves and fittings multiplies welds, contact surfaces and potential dead legs, all of them liabilities in hygienic service.
- One machined body: Integrating the valves into a single machined body serves several piping schemes with one assembly.
- Less hold-up volume: Hold-up volume drops dramatically and the installed footprint shrinks.
- Easier validation: Fewer surfaces and joints also mean simpler cleaning, less product loss and an easier validation package compared with a fabricated valve cluster.
Where It's Used
- Column switching: It is designed for chromatography column switching in biopharmaceutical purification suites.
- Replaces a valve group: It handles the routing duties that normally require a group of valves around the column.
- Downstream processing: It suits downstream processing steps where the product is valuable and every bit of recovery and cleanliness matters.
Good to Know
- Two block variants: One block carries an integral bypass valve and one does not, so the assembly can be matched to the piping scheme.
- Patented design: The block design is patented.
- 316L and special alloys: Bodies come in 316L stainless steel, with special alloys such as AL6XN and Hastelloy available on request.
- Hygienic connections: Connections cover hygienic tubing in common gauges, DIN/ISO standards and Tri-Clover Tri-Clamp ends.
- Common spares: Standard Pure-Flo topworks and diaphragms are used, keeping spares common with the rest of a Pure-Flo installation.
